cis-ACPD
CAS No. : 477331-06-9
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| Cat. No. : | HY-19434A |
| M.Wt: | 173.17 |
| Formula: | C7H11NO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively[1][2].
In Vitro:cis-ACPD is a selective group II mGluR agonist, with EC50s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively[2].
cis-ACPD (1-1000 µM; 60 min) stimulates hydrolysis of 3H-phosphoinositide[1].
In Vivo:cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats[1].
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