Obtusifolin


CAS No. : 477-85-0

477-85-0
Price and Availability of CAS No. : 477-85-0
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1mg $80 In-stock
5mg $240 In-stock
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Cat. No. : HY-N2098
M.Wt: 284.26
Formula: C16H12O5
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 477-85-0 :

Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway[1]. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein[2]. In Vitro: Obtusifolin (1, 10, 100 μM) inhibits MUC5AC gene expression induced by EGF, PMA, or TNF-α in NCI-H292 cells[1].

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