NEP(1-40)
CAS No. : 475221-20-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $400 | In-stock |
| 5mg | $1000 | In-stock |
| 10mg | $1500 | In-stock |
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| Cat. No. : | HY-P1242 |
| M.Wt: | 4625.11 |
| Formula: | C206H324N56O65 |
| Purity: | >98 % |
| Solubility: | H2O : 4.17 mg/mL (ultrasonic;adjust pH to 2 with 1M HCl);DMSO : < 1 mg/mL (ultrasonic) |
NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition[1]. In Vivo: NEP(1-40) (89 μg/kg, ip, 15 min and 19 h post-injury) administration further shifts distributions of microglia away from an injury-induced activated morphology towards greater proportions of rod and macrophage-like morphologies[1].
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