BAN ORL 24 (free base)
CAS No. : 475150-69-7
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| Cat. No. : | HY-13222A |
| M.Wt: | 433.59 |
| Formula: | C27H35N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
BAN ORL 24 free base is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 free base has antagonistic effect for nociceptin (NOP) receptor with KI value of 0.24 nM in CHO cell. BAN ORL 24 free base can be used for the research of cancer and analgesic[1]. In Vitro: BAN ORL 24 has antagonist for NOR and MOR (opioid receptor subtype) with IC50 values of 50 μM and 0.224 μM, respectively[2]. In Vivo: BAN ORL 24 (10 mg/kg; i.v.) attenuates the duration of BPRIM97 thermal antinociception[3].
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