Azaleucine


CAS No. : 4746-36-5

4746-36-5
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Cat. No. : HY-121047
M.Wt: 132.16
Formula: C5H12N2O2
Purity: >98 %
Solubility:
Introduction of 4746-36-5 :

Azaleucine is an inhibitor of leucyl-tRNA synthetase. Azaleucine acts as an alternative substrate for this enzyme, undergoes pyrophosphate exchange reaction, and competes with leucine for the active site of the enzyme[1]. In Vitro:DL-azaleucine (10 mM) serves as an alternative substrate for leucyl-tRNA synthetase from Aesculus hippocastanum cotyledons, supporting 20% of the pyrophosphate exchange activity seen with leucine at a concentration of 10 mM[1].

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