15-A2t-Isoprostane
CAS No. : 474391-66-7
(Synonyms: 8-iso Prostaglandin A2)
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| Cat. No. : | HY-114892 |
| M.Wt: | 334.45 |
| Formula: | C20H30O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
15-A2t-Isoprostane (8-iso Prostaglandin A2) is an isoprostaglandin produced by the non-enzymatic oxidation of arachidonic acid[1][2][3].
In Vitro:15-A2t-Isoprostane (10, 30 μM, 3 h) enhances glutamate-induced cytotoxicity and decreases glutathione (GSH) levels in HT22 hippocampus cells[2].
15-A2t-Isoprostane (10 μM, 24 h) inhibits VEGF induced human coronary endothelial cell migration and tubule formation[3].
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