24(S)-Hydroxycholesterol
CAS No. : 474-73-7
(Synonyms: 24S-OHC; 24S-HC; Cerebrosterol)
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| 10mg | $600 | In-stock |
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| Cat. No. : | HY-16940 |
| M.Wt: | 402.65 |
| Formula: | C27H46O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 0.1 mg/mL (ultrasonic;warming);Ethanol : 20 mg/mL (ultrasonic;warming) |
24(S)-Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S)-Hydroxycholesterol (24S-OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24(S)-Hydroxycholesterol (24S-OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism that does not overlapthat of other allosteric modulators[1][2][3].
In Vitro:24(S)-Hydroxycholesterol (1, 10, 30 μM) can protect isolated rat retina from damage caused by elevated hydrostatic pressure[4].
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