(E)-10-Hydroxynortriptyline
CAS No. : 47132-16-1
(Synonyms: E-10-OH-NT)
| Size | Price | Stock |
|---|---|---|
| 1mg | $160 | In-stock |
| 5mg | $400 | In-stock |
| 10 mg | Get quote | |
| 50 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-U00050 |
| M.Wt: | 279.38 |
| Formula: | C19H21NO |
| Purity: | >98 % |
| Solubility: | H2O : 3.57 mg/mL (ultrasonic;warming;heat to 60°C);Methanol : ≥ 25 mg/mL |
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a blood-brain barrier-permeable norepinephrine uptake inhibitor. (E)-10-Hydroxynortriptyline effectively promotes central norepinephrine neuronal transmission, with little interindividual variation in in vivo potency. (E)-10-Hydroxynortriptyline has low affinity for muscarinic receptors, exhibits only extremely weak anticholinergic activity, and does not inhibit salivary secretion. (E)-10-Hydroxynortriptyline can be used in studies related to depression[1][2].
In Vitro:(E)-10-Hydroxynortriptyline inhibits noradrenaline uptake in vitro with 50% of the potency of nortriptyline[1].
(E)-10-Hydroxynortriptyline inhibits noradrenaline uptake into rat brain neurons in vitro with mean activity equal to 57% of nortriptyline's activity, and is equipotent to the Z-10-hydroxynortriptyline (HY-100646A) isomer[2].
(E)-10-Hydroxynortriptyline binds to rat brain muscarinic receptors in vitro with 1/18 the affinity of nortriptyline[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- (E)-10-Hydroxynortriptyline
- Cat. No.:
- HY-U00050
- Quantity:
Your information is safe with us.