| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $230 | In-stock |
| 50mg | $370 | In-stock |
| 100mg | $600 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-112914 |
| M.Wt: | 363.21 |
| Formula: | C16H15BrN2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 83.33 mg/mL (ultrasonic) |
mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy[1].
IC50 & Target:mTOR[1]
In Vitro:mTOR inhibitor-1 (48 h) inhibits proliferation of A549 cells (IC50: 3.176 μM), and delays S phase progression[1].
mTOR inhibitor-1 (0-12.8 μg/mL, 24 h) decreases the level of activated mTOR (p-mTORser2448) in A549 cells[1].
mTOR inhibitor-1 (3.6 μg/mL, 24 h) induces autophagosomes production in the cytoplasm of A549 cells, and accumulates LC3 puncta[1].
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