mTOR inhibitor-1


CAS No. : 468747-17-3

468747-17-3
Price and Availability of CAS No. : 468747-17-3
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5mg $70 In-stock
10mg $115 In-stock
25mg $230 In-stock
50mg $370 In-stock
100mg $600 In-stock
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Cat. No. : HY-112914
M.Wt: 363.21
Formula: C16H15BrN2O3
Purity: >98 %
Solubility: DMSO : 83.33 mg/mL (ultrasonic)
Introduction of 468747-17-3 :

mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy[1]. IC50 & Target:mTOR[1] In Vitro:mTOR inhibitor-1 (48 h) inhibits proliferation of A549 cells (IC50: 3.176 μM), and delays S phase progression[1].
mTOR inhibitor-1 (0-12.8 μg/mL, 24 h) decreases the level of activated mTOR (p-mTORser2448) in A549 cells[1].
mTOR inhibitor-1 (3.6 μg/mL, 24 h) induces autophagosomes production in the cytoplasm of A549 cells, and accumulates LC3 puncta[1].

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