| Size | Price | Stock |
|---|---|---|
| 5mg | $92 | In-stock |
| 10mg | $139 | In-stock |
| 25mg | $249 | In-stock |
| 50mg | $387 | In-stock |
| 100mg | $599 | Get quote |
| 250mg | $1019 | Get quote |
| 500 mg | Get quote | |
| 1 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-123840 |
| M.Wt: | 348.37 |
| Formula: | C20H17FN4O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
MRK-623 (Compound 14k) is an orally active, high-affinity GABAA receptor agonist, with the Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively. MRK-623 shows anxiolytic effect[1]. In Vitro: MRK-623 shows efficacy at human GABAA receptor subtypes expressed in L(tk-) cells measured by whole cell patch-clamp electrophysiology[1]. In Vivo: MRK-623 (oral gavage; 0.3, 1, and 3 mg/kg; once) shows anxiolytic effects in the rat elevated plus maze assay[1].
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