MRK-623


CAS No. : 461449-78-5

461449-78-5
Price and Availability of CAS No. : 461449-78-5
Size Price Stock
5mg $92 In-stock
10mg $139 In-stock
25mg $249 In-stock
50mg $387 In-stock
100mg $599 Get quote
250mg $1019 Get quote
500 mg Get quote
1 g Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-123840
M.Wt: 348.37
Formula: C20H17FN4O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 461449-78-5 :

MRK-623 (Compound 14k) is an orally active, high-affinity GABAA receptor agonist, with the Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively. MRK-623 shows anxiolytic effect[1]. In Vitro: MRK-623 shows efficacy at human GABAA receptor subtypes expressed in L(tk-) cells measured by whole cell patch-clamp electrophysiology[1]. In Vivo: MRK-623 (oral gavage; 0.3, 1, and 3 mg/kg; once) shows anxiolytic effects in the rat elevated plus maze assay[1].

Your information is safe with us.