A-423579


CAS No. : 461045-17-0

461045-17-0
Price and Availability of CAS No. : 461045-17-0
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Cat. No. : HY-12192
M.Wt: 385.45
Formula: C22H25F2N3O
Purity: >98 %
Solubility:
Introduction of 461045-17-0 :

A-423579 is an orally active non-imidazole histamine H3 receptor antagonist. A-423579 exhibits high affinity and good selectivity for human and rat H3 receptors, and possesses both antagonistic and inverse agonistic activities. A-423579 can effectively reduce body weight in obese rodents, with concomitant decreases in fat content, plasma leptin levels, and triglycerides. A-423579 possesses anti-obesity activity and can be used in the research of obesity and related metabolic disorders[1][2].

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