Eact
CAS No. : 461000-66-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $288 | In-stock |
| 50mg | $490 | In-stock |
| 100mg | $784 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103368 |
| M.Wt: | 428.50 |
| Formula: | C22H24N2O5S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Eact is a selective and potent activator of TMEM16A, directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity[1]. In Vitro: Eact elicits both itch-and pain- related behaviours in a TRPV1-dependent manner. Eact activates membrane currents in mTRPV1-expressing HEK293T cells in a concentration-dependent manner with an EC50 of 11.6 ± 2.5 μM. TMEM16A activator Eact activates both native and recombinant TRPV1 channels[1].
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