ML192
CAS No. : 460331-61-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $170 | In-stock |
| 10mg | $275 | In-stock |
| 25mg | $550 | In-stock |
| 50mg | $880 | In-stock |
| 100mg | $1400 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-122246 |
| M.Wt: | 382.48 |
| Formula: | C20H22N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
ML192 is a selective ligand antagonist of GPR55. ML192 inhibits the β-arrestin trafficking, ERK1/2 phosphorylation and PKCβII translocation[1].
In Vitro:ML192 inhibits the β-arrestin trafficking induced by 10 μM L-α lysophosphatidylinositol (LPI) or 1 μM ML186 with IC50 values of 0.70 µM and 0.29 µM, respectively[1].
ML192 significantly inhibits ERK1/2 phosphorylation in GPRSS-expressing U2OS cells with an IC50 value of 1.1 µM[1].
ML192 (0, 10, 30 and 100 µM) reduces the translocation of PKCβII in cells with the Wild-Type GPR55 receptor[1].
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