MK-0493


CAS No. : 455956-93-1

455956-93-1
Price and Availability of CAS No. : 455956-93-1
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1mg $195 In-stock
5mg $430 In-stock
10mg $690 In-stock
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Cat. No. : HY-118930
M.Wt: 546.09
Formula: C30H38ClF2N3O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 455956-93-1 :

MK-0493 is an orally active melanocortin-4 receptor (MC4R) agonist. MK-0493 reduces food intake, suppresses weight gain, elevates blood pressure at high doses, and exhibits preclinical erectile regulatory activity. MK-0493 can be used in research related to obesity[1][2]. In Vivo:MK-0493 (20-60 mg/kg/day; daily) reduces overnight food intake by 34% in wild-type mice, by ~20-30% in diet-induced obese mice, and induces weight loss in diet-induced obese mice, while showing no effect in Mc3r/4r double-knockout mice[1].

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