ML148


CAS No. : 451496-96-1

451496-96-1
Price and Availability of CAS No. : 451496-96-1
Size Price Stock
1mg $70 In-stock
5mg $207 In-stock
10mg $324 In-stock
25mg $585 In-stock
50mg $855 In-stock
100mg $1215 In-stock
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Cat. No. : HY-123548
M.Wt: 319.40
Formula: C20H21N3O
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 451496-96-1 :

ML148 is a potent and selective 15-PGDH inhibitor with an IC50 of 56 nM. ML148 has the potential for the research of prostaglandin-signaling pathways[1]. IC50 & Target: IC50: 56 nM (15-PGDH)[1] In Vitro: ML148 (compound 13) shows selectivity with IC50s of 56, 36000, >57500, >57500 nM for 15-PGDH, ALDH1A1, HADH2, HSD17β4, respectively[1].
ML148 (10, 20 nM) decrease Vmax by 25% and reduces the apparent Km by half at a concentration of 10 nM[1].

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