| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $207 | In-stock |
| 10mg | $324 | In-stock |
| 25mg | $585 | In-stock |
| 50mg | $855 | In-stock |
| 100mg | $1215 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-123548 |
| M.Wt: | 319.40 |
| Formula: | C20H21N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C) |
ML148 is a potent and selective 15-PGDH inhibitor with an IC50 of 56 nM. ML148 has the potential for the research of prostaglandin-signaling pathways[1].
IC50 & Target: IC50: 56 nM (15-PGDH)[1]
In Vitro: ML148 (compound 13) shows selectivity with IC50s of 56, 36000, >57500, >57500 nM for 15-PGDH, ALDH1A1, HADH2, HSD17β4, respectively[1].
ML148 (10, 20 nM) decrease Vmax by 25% and reduces the apparent Km by half at a concentration of 10 nM[1].
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