RepSox
CAS No. : 446859-33-2
(Synonyms: E-616452; SJN 2511)
| Size | Price | Stock |
|---|---|---|
| 5mg | $77 | In-stock |
| 10mg | $99 | In-stock |
| 25mg | $220 | In-stock |
| 50mg | $385 | In-stock |
| 100mg | $660 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-13012 |
| M.Wt: | 287.32 |
| Formula: | C17H13N5 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic) |
RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes[1][2].
IC50 & Target:IC50: 4 nM (ALK5 autophosphorylation)[1]
In Vitro:RepSox (compound 19) inhibits ALK5 autophosphorylation with an IC50 value of 4 nM[1].
RepSox (0-10?μM; 0-8 days) induces adipogenesis from mouse embryonic fibroblasts (MEFs) in fibroblast culture medium[2].
RepSox (0-10?μM; 0-8 days) promotes the differentiation of the brown fat precursor cells and induce browning of the white fat precursor cells[2].
RepSox(0-10?μM; 0-8 days) induces brown adipogenesis in primary mouse fibroblasts and fat precursor cells[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- RepSox
- Cat. No.:
- HY-13012
- Quantity:
Your information is safe with us.