Alisol F 24-acetate
CAS No. : 443683-76-9
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| Cat. No. : | HY-107315 |
| M.Wt: | 530.74 |
| Formula: | C32H50O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Alisol F 24-acetate is a triterpene compound that can be isolated from the rhizomes of Alisma orientalis. Alisol F 24-acetate inhibits the secretion of HBV surface antigen HBsAg and HBeAg with IC50 values of 7.7 µM and 5.1 µM. Alisol F 24-acetate has proapoptotic activity and can be used for cancer research[1][2].
In Vitro:Alisol F 24-acetate (5, 10 and 20 µM; 24 h) increases the chemosensitivity of Doxorubicin (HY-15142A) with dose-dependent manner in MCF-7/DOX cells[2].
Alisol F 24-acetate (5, 10 and 20 µM) increases the accumulation of doxorubicin with dose-dependent manner in MCF-7/DOX cells. Alisol F 24-acetate (10 µM) increases absorption of Digoxin (HY-B1049) (AP-BL) and decreases secretion of digoxin (BL-AP) in the Caco-2 cell monolayer[2].
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