Aurintricarboxylic acid (Standard)
CAS No. : 4431-00-9
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| Cat. No. : | HY-122575R |
| M.Wt: | 422.34 |
| Formula: | C22H14O9 |
| Purity: | >98 % |
| Solubility: |
Aurintricarboxylic acid (Standard) is the analytical standard of Aurintricarboxylic acid. This product is intended for research and analytical applications. Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively[1]. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase[2]. Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis[3]. Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway[4]. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM[5]. Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 μM[6]. IC50 & Target:IC50: 8.6 nM (rP2X1R)[1], 72.9 nM (rP2X3R)[1], influenza viruses[2], topoisomerase II[3], apoptosis[3]
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