NCGC00092410
CAS No. : 442898-34-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $121 | In-stock |
| 10mg | $198 | In-stock |
| 25mg | $385 | In-stock |
| 50mg | $605 | In-stock |
| 100mg | $935 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-114043 |
| M.Wt: | 353.46 |
| Formula: | C21H27N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 41.67 mg/mL (ultrasonic) |
NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC) inhibitor, with an IC50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 μM. NCGC00092410, a GC chaperone, and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease[1].
IC50 & Target:IC50: 31 nM (glucocerebrosidase)[1]
In Vitro: NCGC00092410 (7.3-130 nM; 25 min) inhibits the GC activity at various substrate concentrations (10-150 μM) in a dose-dependent manner[1].
NCGC00092410 (55-40 μM; 2 d) increases the GC activity in the N370S mutant fibroblasts[1].
NCGC00092410 (40 μM; 60-72 h) increases the lysosomal localization of GC in gaucher fibroblasts[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- NCGC00092410
- Cat. No.:
- HY-114043
- Quantity:
Your information is safe with us.