FR260330
CAS No. : 442198-67-6
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| 5mg | $894 | Get quote |
| 10mg | $1306 | Get quote |
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| Cat. No. : | HY-122063 |
| M.Wt: | 617.02 |
| Formula: | C29H28ClF3N6O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
FR260330 is a selective, orally active inhibitor for inducible nitric oxide synthase (iNOS) through suppression of iNOS dimerization. FR260330 inhibits the NO accumulation in rat splenocytes and human DLD-110 cells, with IC50 of 27 and 10 nM. FR260330 ameliorates the Lipopolysaccharides (HY-D1056)-induced inflammatory diseases in rats model[1].
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