Besifovir


CAS No. : 441785-25-7

(Synonyms: LB80331)

441785-25-7
Price and Availability of CAS No. : 441785-25-7
Size Price Stock
5mg $170 In-stock
10mg $270 In-stock
25mg $480 In-stock
50mg $720 In-stock
100mg $1120 In-stock
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Cat. No. : HY-19447
M.Wt: 299.22
Formula: C10H14N5O4P
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL
Introduction of 441785-25-7 :

Besifovir (LB80331), a parent drug converted by LB80380 (HY-19447A), further metabolizes to its active form, LB80317 (HY-106235). Besifovir is an orally active, novel antiviral agent against hepatitis B virus (HBV)[1][2]. In Vivo:The prodrug, LB80380, is rapidly absorbed after oral administration (30, 60, 120, 240 mg) and is converted to its parent drug, Besifovir (LB80331) (LB80380 was not detected in plasma). The median Tmaxs of LB80331 ranged from 1.0 to 2.0 h postdosing. Thereafter, the plasma LB80331 concentration declined in a monoexponential manner, and the mean values of t1/2 ranged from 2.5 to 3.3 h[2].

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