Monomethyl phthalate


CAS No. : 4376-18-5

(Synonyms: 2-(Methoxycarbonyl)benzoic acid)

4376-18-5
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Cat. No. : HY-Y1097
M.Wt: 180.16
Formula: C9H8O4
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 4376-18-5 :

Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats[1][2][3]. In Vitro:Monomethyl phthalate (2.5-100μg/mL, 3 h) increases the erythrocyte hemolysis rate[3]. In Vivo:Monomethyl phthalate (1.3-128.7 mg/L) affects the survival rate and sex ratio of young frogs, but has no significant adverse effect on the health of adult frogs[2].
Monomethyl phthalate (5-250 mg/kg, p.o., daily for 21 day) causes damage to erythrocytes after entering the organism[3].

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