Coumetarol
CAS No. : 4366-18-1
(Synonyms: Dicumoxane; Ph 137)
| Size | Price | Stock |
|---|---|---|
| 5mg | $81 | In-stock |
| 10mg | $135 | In-stock |
| 25mg | $270 | In-stock |
| 50mg | $430 | In-stock |
| 100mg | $666 | In-stock |
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| Cat. No. : | HY-U00017 |
| M.Wt: | 380.35 |
| Formula: | C21H16O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Coumetarol (Dicumoxane) is a vitamin K antagonist. IC50 & Target: vitamin K[1] In Vitro: Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent[1].
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