Ajmaline
CAS No. : 4360-12-7
(Synonyms: Cardiorythmine; (+)-Ajmaline)
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| 100mg | $50 | In-stock |
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| Cat. No. : | HY-B1167 |
| M.Wt: | 326.43 |
| Formula: | C20H26N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia[1][2]. In Vitro: Electrophysiological experiments are performed with human embryonic kidney (HEK) cells (whole-cell patch clamp) and Xenopus oocytes (double-electrode voltage clamp) expressing wild-type and mutant HERG channels. Ajmaline blocks HERG currents with an IC50 of 1.0μM in HEK cells and 42.3μM in Xenopus oocytes[2].
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