Atecegatran
CAS No. : 433937-74-7
(Synonyms: AR-H067637)
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| Cat. No. : | HY-10275 |
| M.Wt: | 466.87 |
| Formula: | C21H21ClF2N4O4 |
| Purity: | >98 % |
| Solubility: |
Atecegatran (AR-H067637) is an orally active competitive thrombin inhibitor with a Ki of 2-4 nM. AR-H067637 inhibits platelet activation and aggregation by blocking thrombin binding to fibrin and thrombomodulin. Atecegatran demonstrates significant anticoagulant effects in various plasma coagulation assays, with an IC50 ranging from 93 to 220 nM. Atecegatran can be used in research related to thromboembolic disorders[1].
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