SMI 6860766
CAS No. : 433234-16-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $122 | Get quote |
| 5mg | $365 | Get quote |
| 10mg | $584 | Get quote |
| 25mg | $1168 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-125025 |
| M.Wt: | 336.61 |
| Formula: | C15H11BrClNO |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
SMI 6860766, a small molecule inhibitor of CD40-TRAF6 interaction, improves glucose tolerance, reduces immune cell accumulation in adipose tissue, and reduces AT inflammation[1].
In Vitro:SMI 6860766 (0-100 μM; 1 h) dose-dependently suppresses CD40-induced gene expression of IL-1β and IL-6 cytokines in BM-derived macrophages[1].
SMI 6860766 reduces the levels of CCL2 in CD40+/+, CD40-Twt and CD40-TRAF2/3/5?/? macrophages[1].
In Vivo:SMI 6860766 increases the number of adipocytes per field of view by 15.3% in mouse EpAT, indicating that SMI reduces adipocyte size, indicating reduces lipid storage and improves metabolic function[1].
SMI 6860766 reduces the number of total leukocytes (CD45+ cells) in mouse EpAT by 68.5%[1].
SMI 6860766 does not induce differences in hepatosteatosis[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- SMI 6860766
- Cat. No.:
- HY-125025
- Quantity:
Your information is safe with us.