VU0038882


CAS No. : 429653-28-1

429653-28-1
Price and Availability of CAS No. : 429653-28-1
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5mg $235 In-stock
10mg $375 In-stock
25mg $750 In-stock
50mg $1200 Get quote
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Cat. No. : HY-118951
M.Wt: 276.29
Formula: C17H12N2O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 429653-28-1 :

VU0038882 is a small-molecule activator of coproporphyrinogen oxidase (CgoX). VU0038882 can activate CgoX from Gram-Positive bacteria in vitro. VU0038882 can be used for the research of skin and soft tissue infections (SSTIs) [1]. In Vitro:VU0038882 (‘882) (40 μM) exposure leads to accumulation of CPIII in S. aureus[1].
VU0038882 (0-10 μM) activates CgoX from Gram-Positive bacteria in vitro[1].
VU0038882 (50 μM) induces photosensitivity in Gram-positive pathogens[1].
VU0038882 leads to massive heme accumulation resulting in HssRS activation in S. aureus[1].
VU0038882 leads to photosensitization of Gram-positive bacteria, reducing bacterial burdens in vivo[1].

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