LY518674
CAS No. : 425671-29-0
(Synonyms: LY-674)
| Size | Price | Stock |
|---|---|---|
| 1mg | $220 | In-stock |
| 5mg | $460 | In-stock |
| 10mg | $680 | In-stock |
| 25mg | $1100 | In-stock |
| 50mg | $1480 | In-stock |
| 100mg | $1990 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-50665 |
| M.Wt: | 409.48 |
| Formula: | C23H27N3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
LY518674 is a potent, selective PPARα agonist, with an EC50 of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis[1][2][3].
IC50 & Target:EC50: 42 nM (human PPARα)[1]
In Vivo:LY518674 reduces triglycerides and increased HDL-C in vivo[2].
LY518674 substantially increases apolipoprotein A-I (apoA-I) turnover without major impact on steady-state levels of apoA-I or high-density lipoprotein-cholesterol (HDL-C) [3].
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