(S)-β-Aminoisobutyric acid


CAS No. : 4249-19-8

4249-19-8
Price and Availability of CAS No. : 4249-19-8
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Cat. No. : HY-113380
M.Wt: 103.12
Formula: C4H9NO2
Purity: >98 %
Solubility: H2O : 250 mg/mL (ultrasonic)
Introduction of 4249-19-8 :

(S)-β-Aminoisobutyric acid is an orally active S-isomer of β-Aminoisobutyric acid (HY-W012974). (S)-β-Aminoisobutyric acid can be produced through the catabolism of thymine and valine. (S)-β-Aminoisobutyric acid reduces apoptosis and increases the ratio of p-AMPK. (S)-β-Aminoisobutyric acid has cardioprotective effects. (S)-β-Aminoisobutyric acid is associated with acute aerobic exercise[1][2][3]. In Vitro:(S)-β-Aminoisobutyric acid (10-30 mM) increases p-AMPK expression in a dose-dependent manner in H9C2 cardiomyocytes[2]. In Vivo:(S)-β-Aminoisobutyric acid (75 mg/kg; p.o.; 8 weeks) improves the cardiac structure and function of rats with heart failure after myocardial infarction[2].

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