Flunixin (meglumine)
CAS No. : 42461-84-7
| Size | Price | Stock |
|---|---|---|
| 500mg | $50 | In-stock |
| 1g | $80 | In-stock |
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| Cat. No. : | HY-B0386 |
| M.Wt: | 491.46 |
| Formula: | C21H28F3N3O7 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL |
Flunixin meglumine is a cyclooxygenase (COX) inhibitor with IC50 values of 0.55 and 3.24 μM for COX-1 and COX-2, respectively. Flunixin meglumine shows anti-inflammatory effects[1][2].
In Vitro:flunixin meglumine (10-1000 μM, 2 h) inhibits lipopolysaccharide (LPS)-induced activity of inducible nitric oxide synthase (iNOS) in RAW 264.7 murine macrophages[2].
flunixin meglumine (10-1000 μM, 2 h) inhibits lipopolysaccharide-induced activation of nuclear factor kappa B (NfκB) in RAW 264.7 murine macrophages[2].
In Vivo:Flunixin meglumine (intravenous injection; 1.1 mg/kg; once) treatment inhibits the formation of exudate PGE2 and serum TXB2[1].
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