Pinostilbene


CAS No. : 42438-89-1

(Synonyms: trans-Pinostilbene)

42438-89-1
Price and Availability of CAS No. : 42438-89-1
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Cat. No. : HY-N3059
M.Wt: 242.27
Formula: C15H14O3
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 42438-89-1 :

Pinostilbene (trans-Pinostilbene) is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells[1]. In Vitro:Pinostilbene (0- 40 μM; 24 hours, 48 hours) does not cause significant inhibition on the growth of normal colon cells[1].
Pinostilbene (20 μM, 40 μM; 24 hours, 48 hours) causes a significant and dose-dependent increase in the percentage of cells in S phase in both HCT116 and HT29 cells compared to the control cells[1].
Pinostilbene at μM also induces a modest increase of cell population in G2/M phase in HT29 cells[1].
Pinostilbene(20 μM, 40 μM; 24 hours, 48 hours) modulates expression of key signaling proteins related to cell proliferation and apoptosis[1].
Pinostilbene also acts as a resveratrol methylated derivative and displays protective effects against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells[2].

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