Adamantanine


CAS No. : 42381-05-5

(Synonyms: 2-Aminoadamantane-2-carboxylic acid)

42381-05-5
Price and Availability of CAS No. : 42381-05-5
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250mg $48 In-stock
1g $171 In-stock
5g $854 In-stock
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Cat. No. : HY-121123
M.Wt: 195.26
Formula: C11H17NO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 42381-05-5 :

Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5[1]. In Vivo: Adamantanine (500 mg/kg, i.p., single dose; 1000 mg/kg, p.o., single dose) is non-toxic in Sprague Dawley rats model as a a finely pulverized suspension[2].

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