Acivicin
CAS No. : 42228-92-2
(Synonyms: AT-125; U-42126)
| Size | Price | Stock |
|---|---|---|
| 1mg | $150 | In-stock |
| 5mg | $460 | In-stock |
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| Cat. No. : | HY-W016586 |
| M.Wt: | 178.57 |
| Formula: | C5H7ClN2O3 |
| Purity: | >98 % |
| Solubility: | H2O : 6.67 mg/mL (ultrasonic) |
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2]. IC50 & Target: γ-glutamyl transpeptidase[1] In Vitro: Acivicin (AT-125; 0.1-50 μM; 5 days) has an IC50 of 0.7 μM in human HepG2 cells[1]. In Vivo: Acivicin (AT-125; 5 mg/kg; IP; twice weekly) reduces urinary γ-GT by 70-78%[3].
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