2'-Deoxyuridine 5'-monophosphate (disodium)


CAS No. : 42155-08-8

(Synonyms: dUMP (disodium))

42155-08-8
Price and Availability of CAS No. : 42155-08-8
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5g $414 In-stock
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Cat. No. : HY-W011142
M.Wt: 352.15
Formula: C9H11N2Na2O8P
Purity: >98 %
Solubility: H2O : 250 mg/mL (ultrasonic);DMSO : < 1 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 42155-08-8 :

2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis[1]. In Vitro:The compounds with anti-bacterial activity against the human pathogenic bacterium Helicobacter pylori markedly inhibit the NADPH oxidation and 2'-Deoxyuridine 5'-monophosphate (dUMP)-forming activities of HpThyX enzyme in vitro[2].

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