Tolonidine


CAS No. : 4201-22-3

4201-22-3
Price and Availability of CAS No. : 4201-22-3
Size Price Stock
5mg $60 In-stock
10mg $100 In-stock
25mg $195 In-stock
50mg $310 In-stock
100mg $490 In-stock
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Cat. No. : HY-B1800
M.Wt: 209.68
Formula: C10H12ClN3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 4201-22-3 :

Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties[1]. In Vivo: In the anesthetized dog, tolonidine administered i.v. decreases the amplitude of ventricular contractions, reduces aortic blood flow and increases peripheral vascular resistances[1].
In the bivagotomized pithed rat, tolonidine induces a long-lasting increase in blood pressure with no secondary hypotension, thus suggesting peripheral sympathomimetic properties[1].

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