5-Nitro-1,10-phenanthroline
CAS No. : 4199-88-6
(Synonyms: 5-NP)
| Size | Price | Stock |
|---|---|---|
| 1g | $15 | In-stock |
| 5g | $40 | In-stock |
| 10g | $67 | In-stock |
| 25g | $149 | In-stock |
| 100g | $595 | In-stock |
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| Cat. No. : | HY-W004570 |
| M.Wt: | 225.21 |
| Formula: | C12H7N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells[1][1].
In Vitro: 5-Nitro-1,10-phenanthroline (25 μM; 24 h) kills naturally resistant intracellular bacteria by inducing autophagy in THP-1 macrophages[2].
5-Nitro-1,10-phenanthroline (1x, 5x, 20x or 50x MIC, MIC=0.78 μM; 1 h) also modulates the host machinery to kill intracellular pathogens by inhibiting mycolic acid biosynthesis of Mtb[2].
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