Trepibutone
CAS No. : 41826-92-0
(Synonyms: AA 149; Supacal)
| Size | Price | Stock |
|---|---|---|
| 5mg | $30 | In-stock |
| 10mg | $45 | In-stock |
| 25mg | $80 | In-stock |
| 50mg | $120 | In-stock |
| 100mg | $180 | In-stock |
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| Cat. No. : | HY-108283 |
| M.Wt: | 310.34 |
| Formula: | C16H22O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Trepibutone (AA 149) increases secretion of bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract. Trepibutone can be used for the research of cholecystitis and functional gastrointestinal disorders[1][2]. In Vitro:Trepibutone (1-1000 μM) markedly relaxes the sphincter of Oddi and duodenum[1]. In Vivo:Trepibutone (1-20 mg/kg; i.v. once) dose-dependently increases bile flow[2]. Trepibutone (10 mg/kg; i.v. 3 h after 14C-erythritol injection) stimulates canalicular bile formation without enhancement of water secretion and inhibition of bile reabsorption in the biliary ductules and ducts[2].
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