KIN59
CAS No. : 4152-77-6
(Synonyms: 5'-O-Tritylinosine; 5'-O-Trityl-inosine)
| Size | Price | Stock |
|---|---|---|
| 5mg | $38 | In-stock |
| 10mg | $60 | In-stock |
| 25mg | $100 | In-stock |
| 50mg | $158 | In-stock |
| 100mg | $250 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-102071 |
| M.Wt: | 510.54 |
| Formula: | C29H26N4O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 16 mg/mL (ultrasonic;warming) |
KIN59 (5’-O-Tritylinosine) is a potent thymidine phosphorylase allosteric inhibitor. KIN59 inhibits FGF2-stimulated cell growth. KIN59 inhibits the expression of p-FGFR1, P-Akt in FGF2 (10 ng/mL) stimulated cells. KIN59 shows anti-tumor activity[1].
In Vitro:KIN59 (0-100 µM; 24 h) inhibits GM7373 cell proliferative with IC50 values of 5.8, 63 µM for FGF2 (30 ng/mL) and PBS (10%) stimulated, respectively[1].
KIN59 (60 µM; 30 min) inhibits the expression of p-FGFR1, P-Akt in FGF2 (10 ng/mL) stimited FGFR1-overexpressing GM7373-FGFR1 cells[1].
KIN59 inhibits recombinant bacterial (E. coli) and human thymidine phosphorylase (TPase) with IC50 values of 44 μM and 67 μM, respectively[2].
In Vivo:KIN59 (15 mg/kg; s.c.; twice daily from day 2 for 20 days) shows anti-tumor activity in mice[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- KIN59
- Cat. No.:
- HY-102071
- Quantity:
Your information is safe with us.