Casopitant
CAS No. : 414910-27-3
(Synonyms: GW679769)
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| Cat. No. : | HY-14405 |
| M.Wt: | 616.61 |
| Formula: | C30H35F7N4O2 |
| Purity: | >98 % |
| Solubility: |
Casopitant (GW679769) is a potent, selective, brain-penetrant and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant antagonizes the emetic effects of Substance P (HY-P0201). Casopitant is also a substrate and weak to moderate inhibitor of CYP3A4. Casopitant is indicated for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV)[1].
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