CAS No. : 41372-08-1
(Synonyms: L-(-)-α-Methyldopa (hydrate); MK-351 (hydrate))
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| Cat. No. : | HY-B0225B |
| M.Wt: | 238.24 |
| Formula: | C10H16NO5.5 |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic);DMSO : 25 mg/mL (ultrasonic) |
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2]. In Vivo: Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment[2].
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