Etodolac
CAS No. : 41340-25-4
(Synonyms: AY-24236)
| Size | Price | Stock |
|---|---|---|
| 50mg | $60 | In-stock |
| 100mg | $84 | In-stock |
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| Cat. No. : | HY-76251 |
| M.Wt: | 287.35 |
| Formula: | C17H21NO3 |
| Purity: | >98 % |
| Solubility: | H2O : 0.67 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL |
Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM) IC50 & Target: IC50: 53.5 nM (COX)[1]. In Vitro: Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other "COX-2 inhibitors." Unlike rofecoxib, both etodolac and celecoxib can fully inhibit COX-1 and are designated as having "preferential selectivity" toward COX-2. The (inactive against COX) r-enantiomer of etodolac inhibits beta-catenin levels in hepatoma cells.
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