Rilapladib
CAS No. : 412950-08-4
(Synonyms: SB 659032)
| Size | Price | Stock |
|---|---|---|
| 5mg | $290 | In-stock |
| 10mg | $470 | In-stock |
| 25mg | $720 | In-stock |
| 50mg | $1000 | In-stock |
| 100mg | $1500 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-102004 |
| M.Wt: | 735.81 |
| Formula: | C40H38F5N3O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 86.67 mg/mL (ultrasonic) |
Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM[1]. Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist[2]. IC50 & Target: IC50: 230 pM (Lp-PLA2)[1]. In Vitro: Rilapladib through reduction of the PAF biological activity (as PAF inhibitors) and PAF levels could reduce Lp-PLA2 biosynthesis and prevent the possible adverse effects of Lp-PLA2[2].
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