Pentaethylene glycol di(p-toluenesulfonate)


CAS No. : 41024-91-3

(Synonyms: Penta(ethylene glycol) bis(p-toluenesulfonate); Bis-Tos-PEG5)

41024-91-3
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Cat. No. : HY-W004447
M.Wt: 546.65
Formula: C24H34O10S2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 41024-91-3 :

Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

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