Sergliflozin etabonate


CAS No. : 408504-26-7

(Synonyms: GW-869682X)

408504-26-7
Price and Availability of CAS No. : 408504-26-7
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5mg $275 In-stock
10mg $410 In-stock
25mg $660 In-stock
50mg $880 In-stock
100mg $1200 In-stock
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Cat. No. : HY-12611
M.Wt: 448.46
Formula: C23H28O9
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 408504-26-7 :

Sergliflozin etabonate (GW-869682X) is a potent and orally active sodium glucose cotransporter (SGLT2) inhibitor. Sergliflozin etabonate shows antidiabetic and antihyperglycemic effects. Sergliflozin etabonate significantly reduces non-fasting blood glucose levels in diabetic mice. Sergliflozin etabonate has the potential for the research of diabetes[1]. In Vivo:Sergliflozin etabonate (1, 3, 10, 30 mg/kg; oral; once) significantly reduces non-fasting blood glucose levels in KK-Ay mice in a dose-dependent manner[1].
Sergliflozin etabonate (1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate; fed; daily for 9 weeks) reduces non-fasting blood glucose level and decreases triglyceride content in the liver in a dose-dependent manner in KK-Ay mice[1].

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