Piperaquine


CAS No. : 4085-31-8

4085-31-8
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Cat. No. : HY-B1896
M.Wt: 535.51
Formula: C29H32Cl2N6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 4085-31-8 :

Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin[1][2]. In Vivo: Piperaquine (10-90 mg/kg; a single i.p.) decreases parasitemia at all of the doses tested in mice[1].
Piperaquine (90 mg/kg; a single i.p.) exhibits the t1/2, apparent clearance, and apparent volume of distribution 17.8 days, 33.5 mg•h/L, 1.55 L/h/kg, and 956 L/kg, respectively, in healthy mice and 16.1 days, 27.3 mg•h/L, 1.9 L/h/kg, and 1,059 L/kg in malaria-infected mice[1].

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