Capsaicin (Purity 65%)


CAS No. : 404-86-4

404-86-4
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Cat. No. : HY-10448A
M.Wt: 305.41
Formula: C18H27NO3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 404-86-4 :

Capsaicin (Purity 65%) is a mixture of Capsaicin and Dihydrocapsaicin (Ratio >2:1). Capsaicin (Purity 65%) is an orally active capsaicin receptor (TRPV1) agonist[1][2]. In Vitro:Capsaicin is the main Capsaicinoid in chili peppers, followed by Dihydrocapsaicin. These two compounds provide about twice hotness to the taste and nerves as the minor capsaicinoids[2]. In Vivo:Capsaicin (Purity 65%) (1-10 mg/kg, oral gavage) increases chlorzoxazone 6-hydroxylase activity and the expression of CYP2E1 in liver microsomes of rats[4].
Capsaicin (Purity 65%) (10 mg/kg, s.c.) shows the Cmax of 104.9 ng/mL for Capsaicin and 54.3 ng/mL for Dihydrocapsaicin, the Tmax of 5 h for Capsaicin and 4 h for Dihydrocapsaicin[5].
Capsaicin is more pungent than Dihydrocapsaicin (HY-N0361)[6].

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