MDL12330A
CAS No. : 40297-09-4
(Synonyms: RMI12330A)
| Size | Price | Stock |
|---|---|---|
| 5mg | $158 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $432 | In-stock |
| 50mg | $695 | In-stock |
| 100mg | $1115 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-103192 |
| M.Wt: | 377.01 |
| Formula: | C23H37ClN2 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic) |
MDL12330A (RMI12330A) is an adenylyl cyclases inhibitor. MDL12330A can inhibit KV channels, increases insulin secretion and Ca2+ levels. MDL12330A accentuates contractions in uterine rings and inhibits cardiac functions. MDL12330A can be used for the research of endocrinology, metabolic and cardiovascular disease [1][2][3].
In Vitro:MDL12330A (10 μM) increases insulin secretion and produces prolonged APDs in pancreatic beta cells[1].
MDL-12,330A (10 μM) inhibits KV channels and increases Ca2+ levels in pancreatic beta cells[1].
MDL12330A (10 μM, 30 min) accentuates contractions in uterine rings from rats at mid gestation but not at term gestation or at term gestation in labor[2].
MDL12330A inhibits all cardiac functions in isolated active hearts of guinea pigs with an IC50 of 1.1 μM, including contractile force, dP/dt, dF/dt, pressure development, and activity performance[3].
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