DR4485 (hydrochloride)


CAS No. : 402942-53-4

402942-53-4
Price and Availability of CAS No. : 402942-53-4
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Cat. No. : HY-103126
M.Wt: 491.88
Formula: C26H29Cl3N2O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 402942-53-4 :

DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14)[1]. IC50 & Target: pKi: 8.14 (5-HT7)[1] In Vitro: DR4485 (MZ54 WT cells; 6 µM or 8 µM) hydrochloride induces autophagy as well as cell death that is diminished by KO of ATG5 and ATG7[2].

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