Glycitin
CAS No. : 40246-10-4
(Synonyms: Glycitein 7-O-β-glucoside)
| Size | Price | Stock |
|---|---|---|
| 5mg | $66 | In-stock |
| 10mg | $86 | In-stock |
| 25mg | $112 | In-stock |
| 50mg | $158 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-N0012 |
| M.Wt: | 446.40 |
| Formula: | C22H22O10 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs)[1][2].
In Vitro:Glycitin (0.01-10 µM; 7 days) increases cell proliferation and promoted osteoblast formation from BMSCs[1].
Glycitin (0, 0.5, 1 and 5 µM) activates the gene expression of Col I and ALP in BMSCs. Glycitin suppresses protein expression of TGF-β and AKT in BMSCs[1].
In Vivo:Glycitin (5-20 mg/kg; intraperitoneal injection; three times (once every 8 h)) could protect lung tissues from LPS-induced inflammation via inhibiting TLR4-mediated NF-κB and MAPKs signaling pathways[2].
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