Kievitone
CAS No. : 40105-60-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $240 | In-stock |
| 5mg | $600 | In-stock |
| 10mg | $960 | In-stock |
| 25mg | $1920 | In-stock |
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| Cat. No. : | HY-123351 |
| M.Wt: | 356.37 |
| Formula: | C20H20O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity[1][2].
In Vitro:Kievitone (0-40 μM; 4 days) inhibits the proliferation of the oestrogen receptor (ER)-positive breast cancer cell lines MCF-7 and T47D and the ER-negative breast cancer cell line SKBR3 (IC50 values 5-18 μM)[2].
Kievitone (0-40 μM; 48 h) inhibits DNA synthesis of MCF-7 cells stimicrolated by insulin-like growth factor 1, insulin-like growth factor 2, basic fibroblast growth factor or transforming growth factor α[2].
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